1. Expect the worse, so if things are better you think your kids are doing fantastic and if they are going crazy you have already mentally prepared for it.
2. Every stop will take f..o...r...e...v...e...r!!!! Especially if they are potty trained/training, I swear Walker took 30 minutes to poop (or at least that's how long it felt)
3. Stopping on the side of the road is a time saver if your kids just need to pee or even if you need to.
4. If you want to be nice plan to make a million stops or be like me and schedule stops every so many hours and make them wait (they'll live, I promise).
5. A portable dvd player is a must, and I must warn you, you might end up hearing the same darn movie over and over, until you eventually tell them that it's broken and they have to pick a new one.
6. If they are being quite, do not and I repeat do not turn around and make eye contact or that nice relaxing quite time will be over.
7. A cleaning caddy is a nice way to put toys snugged nicely between two car seats and will keep you from constantly turning around to give them something..
8. Make sure you have their favorite blanket or animal.
9. You don't sleep well in the car so don't expect your kids to either.
10. Bring an extra towel incase one of them decides to throw up. and you have to use their favorite blanket to clean it up. Also if you have kids that like to return everything they have eaten plus more, make sure you have extra clothes easily accessible.